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In Praise of Fat

Well, great balls of fat.  Cells have spherical globs of lipid (fat) molecules that never had gotten much attention nor respect.  They have been called lipid droplets, oil bodies, fat globules and other names suggesting they were just the beer bellies of the cell.  Not any more.  Scientists have been taking a closer look at […]

Precision of Cell Quality Control Described

Two research papers in Molecular Cell give more glimpses into the precision of cellular controls to ensure mistakes are detected and weeded out before harm occurs.  Vogel, Bukau and Mayer1 found that the molecular “chaperone” Hsp70 has a “proline switch,” found in all living organisms.  This switch regulates when the polypeptide needing to be folded […]

Soil Provides Library of Antibiotic Resistance

The “evolution of antibiotic resistance” is a staple in the creation-evolution debates, providing evolutionists with a living illustration of evolution taking place right before our eyes.  What if all the information for antibiotic resistance, however, already exists in a library from which bacteria can find it?  That seems to be the implication of a study […]

Health Depends on Robust Cell Machinery

When we think of health, we typically visualize the big things: firm muscles, energy, lack of a protruding stomach and the like.  Cell biology, though, is showing us how our health depends on the proper functioning of countless myriads of molecular machines.  Here are some recent samples from the science journals: Heroic Underdogs in the […]

Minimal Cell More Complex Than Expected

Craig Venter’s lab has been working on an interesting project in theoretical biology: what is the minimum set of genes needed for life?  They have taken one of the simplest organisms, Mycoplasma genitalium, and knocked out genes to see which ones are essential and which are nonessential for viability.  (This is part of the “top […]
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