Mutation Rate Catastrophe: You Cant Even Break Even
April 9, 2007
In a tortoise-and-hare kind of story, a team of geneticists figured out what happens when positive natural selection tries to outrun mutations: “mutation rate catastrophe.” Publishing in PNAS,1 they described how beneficial mutations might become established in a population rapidly (that’s the hare). Eventually (this is the tortoise), harmful mutations accumulate to the tipping point, […]
