June 11, 2008 | David F. Coppedge

Few Typos Get Past Your Spell Checker

Inside your cells are thousands of spell checkers that put any human typist to shame.  In a process critical to all living things, RNA Polymerase II transcribes DNA into RNA rapidly with high fidelity.  Even very similar chemical letters are accurately discriminated by this wonder of a molecular machine that is described in Science Daily.
    The article describes its performance as “exquisite precision” and “unerring accuracy.”  RNA Polymerase II (Pol II) has been studied for years (01/10/2003, 01/05/2006), but new secrets continue to pour forth.  Two teams found out more details about how the proofreading works.  Mutations, they found, caused severe losses in fidelity.  “The researchers said their findings not only offer unprecedented details about the fidelity mechanism of Pol II, but likely about fidelity in all cellular genetic copying machines.
    What?  You mean there’s more?  Absolutely (03/21/2002).  From transcription to translation, each stage of protein manufacture from the DNA template is checked for errors by molecular machines (03/22/2002, 05/17/2002, 06/13/2002, 01/19/2005, 03/31/2005).  When those machines break down due to mutations, bad things happen.  The last word: “As DNA polymerase is responsible for gene replication, the result of its malfunction could be a burst of gene mutation causing an ‘error catastrophe’ that could lead to genome instability and cancer formation.

This is the science of intelligent design (ID) at work (05/18/2005).  No mention of the E-word evolution was heard in these labs (cf. 06/17/2002).  The researchers were hot on the heels of major discoveries about how biological machines achieve phenomenal accuracy.  And at what do they achieve phenomenal accuracy?  the translation of coded information (12/17/2007).  Information is a very ID-friendly word.  Evolutionists speak very little about information.  What can they say?  that material particles subject to various non-intelligent forces built the most accurate code-storage and translation mechanisms known in nature?  How long would it take Lenski to evolve that? (see next story).  Let’s take off the Darwin leg irons and propel science full speed into the Information Age.

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