SCT: Intelligent Design Wins a Nobel Prize
This article by the CEH editor
discusses the 2025 Nobel Prize
for Physiology or Medicine
Posted at Science & Culture Today
Biological Foresight Wins Nobel Prize
by David Coppedge
Science & Culture Today, October 9, 2025
The Nobel Prize for Physiology or Medicine for 2025 was awarded to three immunologists who discovered regulatory T cells and figured out how they prevent autoimmune diseases. Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi will share the coveted $1 million prize that the Nobel Committee announced on October 6 after the winners had been notified. Actually, Ramsdell missed the call because he was off-grid on a hiking trip in the northwest states at the time, but he learned about it from his wife soon after.
Sakaguchi, a researcher at the University of Osaka, Japan, was the first to discover in 1995 that a small population of T cells didn’t fit the paradigm. The Nobel Committee says that he had to think outside the box on the subject of immune tolerance:
Shimon Sakaguchi was swimming against the tide in 1995, when he made the first key discovery. At the time, many researchers were convinced that immune tolerance only developed due to potentially harmful immune cells being eliminated in the thymus, through a process called central tolerance. Sakaguchi showed that the immune system is more complex and discovered a previously unknown class of immune cells, which protect the body from autoimmune diseases. [Italics in original; bold added.]
He had discovered regulatory T cells, abbreviated Treg cells or Tregs, that monitor the other T cells on patrol attacking invaders….
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