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Maxwell’s Demon Helps Run Your Muscles

James Clerk Maxwell once speculated that the second law of thermodynamics could be violated if an agent or “demon” could sort the hot and cold molecules at a barrier, thus overcoming the tendency toward thermal equilibrium.  Something like this has been found at work in the molecular machines in our muscles.  The actin-myosin motor is […]

Search for Intraterrestrial Life Scores Big

Single-celled organisms may be tiny, but what they lack in bulk they make up for in volume and importance.  Scientists have been appreciating more than ever the ubiquitous presence of microbes on our planet and the roles they play to sustain the biosphere.     PhysOrg reported that half of the world’s life may lie […]

Robotic Pothole Crew Keeps Your Genetic Highways in Good Repair

What a thought – a repair crew of molecular machines roaming the strands of your DNA, fixing errors 24 x 7.  It happens.  New techniques are showing the machines jumping from strand to strand like fleas, stopping at suspicious points, and fixing errors, reported Science Daily.  Dr. Bennett Van Houten (U of Pittsburgh Cancer Institute) […]

What Good Is Natural Selection without Progress?

Three papers recently claim to have seen natural selection.  None of them, however, identified a functional advantage that would have tied changes to novel benefits that could improve a species.  Yeast:  “New Type of Genetic Variation Could Strengthen Natural Selection,” trumpeted a headline in Science Daily.  It was about a study of two varieties of […]

Life Crams Stuff on the Long Road

This quote from UC Berkeley wins Stupid Evolution Quote of the Week: In the long evolutionary road from bacteria to humans, a major milestone occurred some 1.5 billion years ago when microbes started building closets for all their stuff, storing DNA inside a nucleus, for example, or cramming all the energy machinery inside mitochondria. Any […]

Life Leads the Way to Invention

Here’s a factoid for the party: a cell is 10,000 times more energy-efficient than a transistor.  PhysOrg tells us that “ In one second, a cell performs about 10 million energy-consuming chemical reactions, which altogether require about one picowatt (one millionth millionth of a watt) of power.”  This and other amazing facts lead to an […]

Molecular Highway Motor Comes into Focus

A beautiful new image of kinesin, a molecular machine that carries cargo on cellular highways, has been produced in greater detail than ever by a team at Berkeley and Brandeis Universities.  Science Daily published a picture and description of how kinesin works.  “Life’s smallest motor – a protein that shuttles cargo within cells and helps […]

Life Is Smarter Than We Know

How can toads calculate?  How can cells without a brain or central nervous system figure out a balanced diet?  How can bugs navigate the wind for optimum flight time?  These are some of the questions that can arise from observations of the living world.  The more we learn about life, the more we find unexpected […]

Life Masters Physics

Living things, especially cells, have mastered the forces of advanced physics in ingenious ways.  This ingenuity sometimes inspires physicists to try to copy it.  Here are some recent examples: Photosynthesis and quantum mechanics:  Nature reported that plants take advantage of quantum mechanics in photosynthesis.1  “The photosynthetic apparatus of cryptophyte algae is odd – its pigments […]

Building a Cell: Staggering Complexity

“The living cell is a self-organizing, self-replicating, environmentally responsive machine of staggering complexity.”  Thus began a special section on “Building a Cell” in Nature last week.1  The section with five papers explores what is known about gene regulation, cell organization and signalling.  It’s an opportunity, as well, to see what scientists think about what they […]

Molecular Machines Use Moving Parts

Research papers into the processes of molecular machines continue to reveal moving parts: “fingers” that open and close, ratchets that lock into place, and feet that move along tracks.  Here are a few samples from the voluminous literature that continues to pour from biophysics labs. DNA Polymerase I:  Scientific papers tend to be reserved in […]

Stem Cell News: Cancer Cures Coming?

Stem cell research has not been as prominent in the popular media lately, but researchers continue to make impressive strides – mostly with adult stem cells.  Science Daily reported the first success treating leukemia with stem cells from umbilical cord blood.  A researcher at the Hutchinson Center said, “The real ground-breaking aspect of this research […]

To Advance Technology, Make Like Nature

Scientists and engineers continue to find the most elegant solutions to practical problems by looking at plants and animals.  Here are a few of the recent examples. Wet computing:  Cells and brains do a superior job of complex processing, so why are our current computers singing how dry I am?  Not for much longer.  Science […]

Best Look Ever at Life’s Smallest Rotary Motor

All cells trade in energy currency called ATP (adenosine triphosphate).  The molecular energy pellets are produced in profusion by molecular machines with rotary engines.  The engines contain all the standard parts: rotor, stator, energy input, and torque production.  They are embedded in the membranes of mitochondria and run on proton motive force.  We’ve reported many […]

DNA Repair Requires Teamwork

As if the genetic code itself was’t incredible enough, researchers have been finding systems that repair it.  There are numerous pathways the cell can embark on to fix DNA errors.  Two key players were recently described in more detail in the journal Science.1     A damaged genetic code is worse than a book with […]
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