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Genetics

Few Mutational Pathways Lead to Darwinian Evolution
April 12, 2006
Mutations may not be as helpful for neo-Darwinian evolution as expected, say researchers from Harvard.  Let’s say five mutations need to occur for a bacterium to gain resistance to an antibiotic, and there are 120 ways to get these mutations.  They found that only about 10 of the pathways could be selected by natural selection.  […]
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Genetics

Isolated DNA Bases Are Destroyed Quickly
April 11, 2006
Without water, DNA bases fall apart quickly.  Any origin-of-life models expecting the building blocks of DNA (nucleotides) to stick around for long are going to suffer, say researchers from Oregon State University.  The molecules can enter a “dark state” in which they are highly vulnerable to UV radiation.  This idea was once considered “scientific heresy” […]
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Genetics

Minimum Genome Doubles
March 31, 2006
How many genes does a bacterium need to live?  Evolutionists interested in the origin of life have been trying to determine the minimal genome for life.  Those estimates may have been way too low, say researchers from the University of Bath.  Though they did not supply a number, they estimate the required number of genes […]
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Cell Biology

Reviewer Stunned by Author’s Handwaving
March 31, 2006
David Nicholls appears to have suffered whiplash from a line in a book he was reviewing in Science,1 Power, Sex, Suicide: Mitochondria and the Meaning of Life by Nick Lane (Oxford, 2006).  Though he liked the book in general, he said this about Lane’s explanation for how the first cell got its power generator: The […]
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Cell Biology

Misfolded Proteins Cause Cascade of Harmful Effects
March 12, 2006
There are a myriad ways a polypeptide chain could collapse into a shapeless mass.
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Cell Biology

Introns Stump Evolutionary Theorists
March 9, 2006
This story is not about Enron and Exxon, but about introns and exons.  The proportions of the scandals they are causing in evolutionary theory, however, may be comparable.     Introns are spacers between genes.  For several decades now, it has been a puzzle why they are there, and why a complex machine called a […]
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Amazing Facts

In Praise of Fat
March 6, 2006
Well, great balls of fat.  Cells have spherical globs of lipid (fat) molecules that never had gotten much attention nor respect.  They have been called lipid droplets, oil bodies, fat globules and other names suggesting they were just the beer bellies of the cell.  Not any more.  Scientists have been taking a closer look at […]
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Fossils

It’s a Long (Roundabout) Way from Amphioxus
February 23, 2006
“Every solution breeds new problems” laments a Murphyism, and Henry Gee feels the pain.  In Nature this week,1 he delved into the growing quandary about where to put the common ancestor of starfish, sea squirts and chordates, including the vertebrates and us human beings.  His challenge is to prove the idiot’s sanity: So, if lancelets […]
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Fossils

Evolutionists Tackle Cambrian Explosion
February 14, 2006
You have to give credit to anyone who tackles a big problem head-on, regardless of whether you agree with their solution.  Two recent papers take on one of evolution’s biggest challenges: the Cambrian Explosion.  Assuming the evolutionary timeline, this represents a “brief” 5 million year period back 530 million years ago when most of the […]
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Cell Biology

Precision of Cell Quality Control Described
February 3, 2006
Two research papers in Molecular Cell give more glimpses into the precision of cellular controls to ensure mistakes are detected and weeded out before harm occurs.  Vogel, Bukau and Mayer1 found that the molecular “chaperone” Hsp70 has a “proline switch,” found in all living organisms.  This switch regulates when the polypeptide needing to be folded […]
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Dumb Ideas

Human Evolution: Clear as Mud
January 24, 2006
Evolutionists speak of our descent from apes with an air of confidence and certainty, but connecting the dots requires a bit of artistic license.  Here are some examples of how any data, no matter how puzzling, can be made to fit the Darwinian picture. Stretchy Clocks:  A famous painting by Salvador Dali portrayed clocks draped […]
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Genetics

Soil Provides Library of Antibiotic Resistance
January 19, 2006
Genetic information that confers antibiotic resistance is already present in the environmental resistome.
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Genetics

Peer Review: Can You Trust a Scientific Journal Paper?
January 9, 2006
Science magazine has egg on its face – deviled, poached, and scrambled – everything but sunny side up.  Last May, it printed one of the biggest breakthrough stories of the year in stem cell research: Korean scientist Woo Suk Hwang, a professor at the Seoul National University and President of the World Stem Cell Hub, […]
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Amazing Facts

Health Depends on Robust Cell Machinery
January 5, 2006
When we think of health, we typically visualize the big things: firm muscles, energy, lack of a protruding stomach and the like.  Cell biology, though, is showing us how our health depends on the proper functioning of countless myriads of molecular machines.  Here are some recent samples from the science journals: Heroic Underdogs in the […]
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Cell Biology

Minimal Cell More Complex Than Expected
January 3, 2006
Craig Venter’s lab has been working on an interesting project in theoretical biology: what is the minimum set of genes needed for life?  They have taken one of the simplest organisms, Mycoplasma genitalium, and knocked out genes to see which ones are essential and which are nonessential for viability.  (This is part of the “top […]
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