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Disease Genes Play the Wrong Tune

How did disease originate?  It might seem that large changes in genes would be required to turn a benign cell into a pathogen, but an article on Science Daily says it might just be a good cell playing a bad tune.     Bacteria have more genes than they use at any one time.  What […]

Evolution as Efficiency Expert

Who would have thought that a lowly bacterium is a “master of industrial efficiency”?  That’s what a researcher at the Weizmann Institute of Science called it.  E. coli, the best-studied microbe, “can be thought of as a factory with just one product: itself,” a press release said.  “It exists to make copies of itself, and […]

What Mean These Observations?

Science news outlets report many interesting findings every week.  It’s not always clear, though, whether the conclusions drawn from them are warranted by the data.  Here are some recent cases: Jaws of steel:  A skull labeled Australopithecus robustus was studied for the force its jaws could generate.  Interpretation: “Early humans had jaws of steel.”  With […]

Obama and Stem Cells: Hope Chest or Pandora’s Box?

Any day now, as he promised, President Obama will likely lift funding restrictions on embryonic stem cell research imposed by former President Bush.  Bush had sought the council of leading scientists and ethicists before making his decision.  Obama, by contrast, will be yielding to the opinions of the scientific societies who have clamored for years […]

New Genetics Revolution Underway

The genetics of the 1950s was that DNA is the seat of all inheritance, and that genetic information traveled one way: from DNA to protein.  That “central dogma” has been changing after decades of further researchers.  Theories of epigenetics (inheritance not limited to DNA) have been gaining attention with increasing frequency.     Science Daily […]

Biology Now Includes Fluid Dynamic Construction

There’s an old legend that Tibetan monks built a wall by levitating heavy stones with sound by beating their drums and gongs.  Something not quite so fantastic but still amazing is done by cells in the embryo.  Scientists have filmed zebrafish embryos using beating cilia to build little stone structures that they use for balance. […]

Nature Struts Darwin Gems

Like a showcase of pearl-handled revolvers, an armory of evidences Nature calls “Darwin’s Gems” have been exhibited to warn creationists that Darwin Day will be defended next month with a show of force.  The authors, Henry Gee (former editor of Nature), Rory Howlett and Philip Campbell have made their 15 Evolutionary Gems freely available “and […]

Handy Motor Found in Virus

Your job today is to stuff a delicate chain into a barrel without breaking it and make it wrap neatly inside.  A tiny virus does this with helping hands, reported Purdue University.  A research team uncovered the mechanism of a “powerful molecular motor” that crams the viral DNA tightly into the capsid with the help […]

Cilium Likened to GPS

A story on Science Daily says that the primary cilium, a protrusion on most human cells that looks like an antenna, acts like a GPS system.  They “orient cells to move in the right direction and at the speed needed to heal wounds, much like a Global Positioning System helps ships navigate to their destinations.” […]

Applying the Scientific Method to Prehistory

What could be more scientific than the scientific method?  A scientist observes an unexplained phenomenon.  He or she gathers data, analyzes it, proposes a hypothesis to explain it, and tests it.  The results are published in a peer-reviewed journal.  Mission accomplished, right?  Here are two papers on very different phenomena – one dealing with the […]

Nature Plagiarizes Behe’s Mousetrap

The prevention of genomic instability – and cancer – can be attributed to a “complex mousetrap” mechanism, said Robert M. Brosh, Jr (Laboratory of Molecular Gerontology, NIH) in Nature.1  This not-so-subtle reference to Michael Behe’s irreducibly complex system described in Darwin’s Black Box even has a mousetrap illustration with the following caption: The BLM protein […]

Far-Out Science

The following list of bizarre stories coming from science news outlets is jarring on two fronts: it shows how little scientists understand, and calls into question what counts as science these days.  Some stories illustrate one or the other; some both. Roar of the aurora aura:  Both Saturn and Mars turned up auroras that are […]

Unique “Orphan Genes” Are Widespread; Have No Evolutionary Explanation

We often hear about the similarities between genomes, but what about the differences?  There’s a growing realization that groups of animals have genetic orphans – genes that are unique to that line (see 01/02/2003).  These genes have no evolutionary homology or kinship to genes from other lineages.  How did they arise?  And what do they […]

Proteins Can Tie Knots

Your job today is to invent a chain that can tie itself in a knot.  The chain can contain little magnets and electrical parts, but when you let go of the ends, a knot will spontaneously form.  This means that one end must form a loop and the other end must thread the loop.  Give […]

Cell Chaperone Is an Optimized Two-Stroke Machine

Proteins need a protected space to fold, and the cell provides it: the GroEL-GroES chaperone (see 05/05/2003, 06/07/2006, and 02/13/2007).  More details keep coming in about this “protein dressing room” as scientists continue to probe its secrets.  Two new papers in PNAS by a team at University of Maryland and College Park reveal that this […]
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